General GLP-1

I’ve been researching GLP-1s for months now and I’m honestly torn. My insurance won’t cover Wegovy or Mounjaro for weight loss (only pre-diabetes), so I’m looking at $1,300-1,500 per month out of pocket. I make decent money but that’s still a huge chunk of my budget. What gets me is that these medications are genuinely…

So I’ve been watching the retatrutide trials closely and the weight loss numbers are honestly insane compared to what I got on Mounjaro. We’re talking potentially 24-26% total body weight loss vs the 15-20% range for tirz. But here’s what’s keeping me up at night – if Zepbound is already hitting $1,500/month at commercial pricing,…

OK so I just saw another interview where a celebrity lost a TON of weight in like 3 months and when asked about it, they said ‘oh you know, just cleaned up my diet and started doing Pilates!’ Like… COME ON. I’ve been doing actual clean eating and working out 5x a week for 6…

So I’ve been on tirzepatide for about 6 months now with pretty good results, but my endo mentioned that there’s literally a whole wave of next-generation stuff coming. Like actual oral GLP-1 pills (not rybelsus which is kinda meh from what I hear), and these triple agonist peptides that hit GLP-1, GIP, AND glucagon receptors…

So I’ve been doing a ton of research and it looks like retatrutide won’t hit the market until at least 2027, maybe even 2028 depending on FDA approval timelines. I’m really interested in it because of the triple receptor action and the trial results look incredible – better weight loss than anything currently available. But…

So I just had my first appointment with a new endocrinologist and I’m honestly confused. I showed him my bloodwork and we talked about my weight loss goals (need to drop about 60lbs, have pre-diabetes). He wants to start me on semaglutide but his plan is to go from 0.25mg straight to 1.0mg after just…

Been thinking about this a lot lately. I started Ozempic in early 2020 for T2D, so I’m coming up on 5 years now. My cousin just started tirzepatide last month and she’s all excited, asking me tons of questions. And it hit me… there are literally MILLIONS of us who’ve been on these drugs for…

So I started tirzepatide back in January at 2.5mg and worked my way up to 10mg. Hit my goal weight last month (down 52 lbs!) and honestly feeling amazing. Had my follow-up appointment yesterday and my doctor wants to drop me back down to 5mg for “maintenance.” She says it’s about finding the minimum effective…

I’ve been on Mounjaro for about 5 months now and the results have been great – down 38 pounds and feeling better overall. But something my nutritionist said last week has been bugging me. She mentioned that GLP-1s slow down gastric emptying and change how our gut processes food, which got me thinking… what is…

So I’ve been on tirzepatide for about 7 months now and I’ve lost 52 pounds which honestly has been life changing. But I keep thinking about what happens next. My doctor basically told me this is a lifetime thing – that if I stop, the weight will likely come back. And I’m sitting here doing…